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January 2005

Last of Days Life Traumatic for Children with Cancer, Study

Cancer is the most common cause of non-accidental death in children. Research by a group of physicians found that little is known about the suffering of children near death from cancer; what their last days are like, and whether they are offered the high quality palliative medication available to dying adults.

   








 
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When cancer strikes, the objective is to cure the child. Thoughts about how toxic the therapies can be, quality of the child’s life, even his growth or her development are less important than the cure. A physician may focus only on that goal even when there is little or no hope. Yet 25% of children with cancer will die from it. Researchers set out to discover how comfortably these children spend their last days, and to learn what the medical community can do to improve the last days of a child with cancer.

Methods

The study was performed in Boston, at a Children's Hospital and at the Dana–Farber Cancer Institute. Physicians interviewed parents of children who died of cancer between 1990 and 1997. Interviews were conducted with one parent from each of 102 families selected between September 1997 and August 1998.

Data was collected using a questionnaire based on a review of literature and opinions of parents and healthcare providers. Parents were asked about their perception of how their child felt during his or her last month of life and the quality of care received by doctors. Researchers also controlled for the parents’ age, sex, race, level of education, annual household income, and religion.


Results

Fatigue, pain, dyspnea (difficulty in breathing), and poor appetite were common problems. The percentage of children who had these symptoms ranged from 19% - constipation and diarrhea - to 57% - fatigue. 89% experienced a lot of suffering from at least one symptom, and 51% from three or more. Children who died of a treatment-related complication suffered more from symptoms than those who did not.

Parents reported that during their last month of life, children:

• had little or no fun-53%

• were more than a little sad-61%

• were not calm and peaceful most of the time-63%

• were often afraid-21%.

70% of parents said their child's death was very peaceful, regardless of the cause.


Conclusions

Researchers determined that the last days of life for children with cancer are very traumatic. They suggested that more attention be made toward symptom control in this population. This might ease the suffering of children in the advanced stages of the disease. The medical community should recognize and improve communication between parents and care givers to help these children during their last days.

Complete findings of the study can be found in The New England Journal of Medicine, Volume 342:326-333, Number 5

Inquiries:

Dr. Weeks at the Center for Outcomes and Policy Research and the Department of Adult Oncology, Dana–Farber Cancer Institute, 44 Binney St., Boston, MA 02115
Email: joanne_wolfe@dfci.harvard.edu.
 


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